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(PDF) Skin melanocytes: Biology and development
WebApr 12, 2024 · Treatment of metastatic melanoma has been revolutionized over the past decade with the emergence of immune checkpoint therapy, but it remains a deadly disease, accounting for 75% of skin cancer deaths despite only making up 5% of skin cancer cases ().Surgical removal of primary melanomas is an effective treatment, with a 99% 5-year … WebMar 30, 2024 · Tyrosinase is a rate-limiting enzyme in melanin biosynthesis and is specifically expressed in differentiated melanocytes. We have identified the enhancer element in the 5′-flanking region of the human tyrosinase gene that is responsible for its pigment cell-specific transcription and have termed it tyrosinase distal element (TDE) … crystal massey midwife
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